Compensatory Hemagglutinin Mutations Alter Antigenic Properties of Influenza Viruses

Influenza viruses routinely acquire mutations in antigenic sites on the globular head of the hemagglutinin (HA) protein. Since these antigenic sites are near the receptor binding pocket of HA, many antigenic mutations simultaneously alter the receptor binding properties of HA. We previously reported...

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Hlavní autoři: Myers, Jaclyn L., Wetzel, Katherine S., Linderman, Susanne L., Li, Yang, Sullivan, Colleen B., Hensley, Scott E.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Microbiology 2013
Témata:
Genetic Diversity and Evolution
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3807274/
https://ncbi.nlm.nih.gov/pubmed/23926344
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01414-13
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