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Recent H3N2 Influenza Virus Clinical Isolates Rapidly Acquire Hemagglutinin or Neuraminidase Mutations When Propagated for Antigenic Analyses

Prior to serological testing, influenza viruses are typically propagated in eggs or cell culture. Recent human H3N2 strains bind to cells with low avidity. Here, we isolated nine primary H3N2 viral isolates from respiratory secretions of children. Upon propagation in vitro, five of these isolates ac...

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Bibliografiske detaljer
Main Authors: Chambers, Benjamin S., Li, Yang, Hodinka, Richard L., Hensley, Scott E.
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology 2014
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4178893/
https://ncbi.nlm.nih.gov/pubmed/24991002
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01077-14
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