Antigenic Drift in H5N1 Avian Influenza Virus in Poultry Is Driven by Mutations in Major Antigenic Sites of the Hemagglutinin Molecule Analogous to Those for Human Influenza Virus

H5N1 highly pathogenic avian influenza virus has been endemic in poultry in Egypt since 2008, notwithstanding the implementation of mass vaccination and culling of infected birds. Extensive circulation of the virus has resulted in a progressive genetic evolution and an antigenic drift. In poultry, t...

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Bibliographische Detailangaben
Hauptverfasser: Cattoli, Giovanni, Milani, Adelaide, Temperton, Nigel, Zecchin, Bianca, Buratin, Alessandra, Molesti, Eleonora, Aly, Mona Meherez, Arafa, Abdel, Capua, Ilaria
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Microbiology 2011
Schlagworte:
Genetic Diversity and Evolution
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3165837/
https://ncbi.nlm.nih.gov/pubmed/21734057
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.02403-10
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