The Human Papillomavirus E6 PDZ Binding Motif Links DNA Damage Response Signaling to E6 Inhibition of p53 Transcriptional Activity

The presence of a PDZ binding motif (PBM) in the human papillomavirus (HPV) E6 oncoprotein appears to be a characteristic marker of high oncogenic potential and confers interaction with a number of different cellular PDZ domain-containing substrates. The E6 PBM is also subject to phosphorylation, re...

Full description

Saved in:
Bibliographic Details
Published in:J Virol
Main Authors: Thatte, Jayashree, Massimi, Paola, Thomas, Miranda, Boon, Siaw Shi, Banks, Lawrence
Format: Artigo
Language:Inglês
Published: American Society for Microbiology 2018
Subjects:
Transformation and Oncogenesis
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6069177/
https://ncbi.nlm.nih.gov/pubmed/29848585
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00465-18
Tags: Add Tag
No Tags, Be the first to tag this record!

Similar Items