The Human Papillomavirus E6 PDZ Binding Motif: From Life Cycle to Malignancy

Cancer-causing HPV E6 oncoproteins are characterized by the presence of a PDZ binding motif (PBM) at their extreme carboxy terminus. It was long thought that this region of E6 had a sole function to confer interaction with a defined set of cellular substrates. However, more recent studies have shown...

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Publicat a:Viruses
Autors principals: Ganti, Ketaki, Broniarczyk, Justyna, Manoubi, Wiem, Massimi, Paola, Mittal, Suruchi, Pim, David, Szalmas, Anita, Thatte, Jayashree, Thomas, Miranda, Tomaić, Vjekoslav, Banks, Lawrence
Format: Artigo
Idioma:Inglês
Publicat: MDPI 2015
Matèries:
Review
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4517114/
https://ncbi.nlm.nih.gov/pubmed/26147797
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/v7072785
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