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Regulation of the Human Papillomavirus Type 18 E6/E6AP Ubiquitin Ligase Complex by the HECT Domain-Containing Protein EDD

Human papillomavirus (HPV) E6 oncoproteins target many cellular proteins for ubiquitin-mediated proteasomal degradation. In the case of p53, this is mediated principally by the E6AP ubiquitin ligase. Several studies have reported that E6 can target certain of its substrates in an apparently E6AP-ind...

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Autors principals: Tomaić, Vjekoslav, Pim, David, Thomas, Miranda, Massimi, Paola, Myers, Michael P., Banks, Lawrence
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology (ASM) 2011
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3067830/
https://ncbi.nlm.nih.gov/pubmed/21228227
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.02004-10
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