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The Human Papillomavirus E6 PDZ Binding Motif Links DNA Damage Response Signaling to E6 Inhibition of p53 Transcriptional Activity

The presence of a PDZ binding motif (PBM) in the human papillomavirus (HPV) E6 oncoprotein appears to be a characteristic marker of high oncogenic potential and confers interaction with a number of different cellular PDZ domain-containing substrates. The E6 PBM is also subject to phosphorylation, re...

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Detalhes bibliográficos
Publicado no:J Virol
Main Authors: Thatte, Jayashree, Massimi, Paola, Thomas, Miranda, Boon, Siaw Shi, Banks, Lawrence
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6069177/
https://ncbi.nlm.nih.gov/pubmed/29848585
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00465-18
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