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Human Papillomavirus 16 (HPV-16), HPV-18, and HPV-31 E6 Override the Normal Phosphoregulation of E6AP Enzymatic Activity

The human papillomavirus (HPV) E6 oncoproteins recruit the cellular ubiquitin ligase E6AP/UBE3A to target cellular substrates for proteasome-mediated degradation, and one consequence of this activity is the E6 stimulation of E6AP autoubiquitination and degradation. Recent studies identified an autis...

詳細記述

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書誌詳細
出版年:J Virol
主要な著者: Thatte, Jayashree, Banks, Lawrence
フォーマット: Artigo
言語:Inglês
出版事項: American Society for Microbiology 2017
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC5660492/
https://ncbi.nlm.nih.gov/pubmed/28835500
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01390-17
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