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Human Papillomavirus 16 (HPV-16), HPV-18, and HPV-31 E6 Override the Normal Phosphoregulation of E6AP Enzymatic Activity
The human papillomavirus (HPV) E6 oncoproteins recruit the cellular ubiquitin ligase E6AP/UBE3A to target cellular substrates for proteasome-mediated degradation, and one consequence of this activity is the E6 stimulation of E6AP autoubiquitination and degradation. Recent studies identified an autis...
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Udgivet i: | J Virol |
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Main Authors: | , |
Format: | Artigo |
Sprog: | Inglês |
Udgivet: |
American Society for Microbiology
2017
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Fag: | |
Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5660492/ https://ncbi.nlm.nih.gov/pubmed/28835500 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01390-17 |
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