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Combinatorial Approaches to Viral Attenuation

Attenuated viruses have numerous applications, in particular in the context of live viral vaccines. However, purposefully designing attenuated viruses remains challenging, in particular if the attenuation is meant to be resistant to rapid evolutionary recovery. Here we develop and analyze a new atte...

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Detalhes bibliográficos
Publicado no:mSystems
Main Authors: Paff, Matthew L., Jack, Benjamin R., Smith, Bartram L., Bull, James J., Wilke, Claus O.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6068830/
https://ncbi.nlm.nih.gov/pubmed/30073203
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/mSystems.00046-18
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