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Combinatorial Approaches to Viral Attenuation

Attenuated viruses have numerous applications, in particular in the context of live viral vaccines. However, purposefully designing attenuated viruses remains challenging, in particular if the attenuation is meant to be resistant to rapid evolutionary recovery. Here we develop and analyze a new atte...

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Bibliografske podrobnosti
izdano v:mSystems
Main Authors: Paff, Matthew L., Jack, Benjamin R., Smith, Bartram L., Bull, James J., Wilke, Claus O.
Format: Artigo
Jezik:Inglês
Izdano: American Society for Microbiology 2018
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC6068830/
https://ncbi.nlm.nih.gov/pubmed/30073203
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/mSystems.00046-18
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