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Engrailed homeoprotein blocks degeneration in adult dopaminergic neurons through LINE‐1 repression
LINE‐1 mobile genetic elements have shaped the mammalian genome during evolution. A minority of them have escaped fossilization which, when activated, can threaten genome integrity. We report that LINE‐1 are expressed in substantia nigra ventral midbrain dopaminergic neurons, a class of neurons that...
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| Publicado no: | EMBO J |
|---|---|
| Main Authors: | , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
John Wiley and Sons Inc.
2018
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6068427/ https://ncbi.nlm.nih.gov/pubmed/29941661 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/embj.201797374 |
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