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Engrailed Homeoprotein Protects Mesencephalic Dopaminergic Neurons from Oxidative Stress

Engrailed homeoproteins are expressed in adult dopaminergic neurons of the substantia nigra. In Engrailed1 heterozygous mice, these neurons start dying at 6 weeks, are more sensitive to oxidative stress, and progressively develop traits similar to those observed following an acute and strong oxidati...

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Shranjeno v:
Bibliografske podrobnosti
izdano v:Cell Rep
Main Authors: Rekaik, Hocine, Blaudin de Thé, François-Xavier, Fuchs, Julia, Massiani-Beaudoin, Olivia, Prochiantz, Alain, Joshi, Rajiv L.
Format: Artigo
Jezik:Inglês
Izdano: 2015
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC5066840/
https://ncbi.nlm.nih.gov/pubmed/26411690
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2015.08.076
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