Engrailed Homeoprotein Protects Mesencephalic Dopaminergic Neurons from Oxidative Stress

Engrailed homeoproteins are expressed in adult dopaminergic neurons of the substantia nigra. In Engrailed1 heterozygous mice, these neurons start dying at 6 weeks, are more sensitive to oxidative stress, and progressively develop traits similar to those observed following an acute and strong oxidati...

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Gepubliceerd in:Cell Rep
Hoofdauteurs: Rekaik, Hocine, Blaudin de Thé, François-Xavier, Fuchs, Julia, Massiani-Beaudoin, Olivia, Prochiantz, Alain, Joshi, Rajiv L.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2015
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5066840/
https://ncbi.nlm.nih.gov/pubmed/26411690
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2015.08.076
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