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Neuroprotective Transcription Factors in Animal Models of Parkinson Disease

A number of transcription factors, including En1/2, Foxa1/2, Lmx1a/b, Nurr1, Otx2, and Pitx3, with key roles in midbrain dopaminergic (mDA) neuron development, also regulate adult mDA neuron survival and physiology. Mouse models with targeted disruption of some of these genes display several feature...

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Detalhes bibliográficos
Publicado no:Neural Plast
Main Authors: Blaudin de Thé, François-Xavier, Rekaik, Hocine, Prochiantz, Alain, Fuchs, Julia, Joshi, Rajiv L.
Formato: Artigo
Idioma:Inglês
Publicado em: Hindawi Publishing Corporation 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4736191/
https://ncbi.nlm.nih.gov/pubmed/26881122
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2016/6097107
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