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Neuroprotective Transcription Factors in Animal Models of Parkinson Disease

A number of transcription factors, including En1/2, Foxa1/2, Lmx1a/b, Nurr1, Otx2, and Pitx3, with key roles in midbrain dopaminergic (mDA) neuron development, also regulate adult mDA neuron survival and physiology. Mouse models with targeted disruption of some of these genes display several feature...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Neural Plast
Hauptverfasser: Blaudin de Thé, François-Xavier, Rekaik, Hocine, Prochiantz, Alain, Fuchs, Julia, Joshi, Rajiv L.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Hindawi Publishing Corporation 2016
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4736191/
https://ncbi.nlm.nih.gov/pubmed/26881122
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2016/6097107
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