Macrophage migration inhibitory factor promotes resistance to MEK blockade in KRAS mutant colorectal cancer cells

Although MEK blockade has been highlighted as a promising antitumor drug, it has poor clinical efficacy in KRAS mutant colorectal cancer (CRC). Several feedback systems have been described in which inhibition of one intracellular pathway leads to activation of a parallel signaling pathway, thereby d...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Julkaisussa:Mol Oncol
Päätekijät: Cheon, Seul‐Ki, Kim, Hwang‐Phill, Park, Ye‐Lim, Jang, Jee‐Eun, Lim, Yoojoo, Song, Sang‐Hyun, Han, Sae‐Won, Kim, Tae‐You
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: John Wiley and Sons Inc. 2018
Aiheet:
Research Articles
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC6068346/
https://ncbi.nlm.nih.gov/pubmed/29896883
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/1878-0261.12345
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