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Hypoxia increases neutrophil-driven matrix destruction after exposure to Mycobacterium tuberculosis

The importance of neutrophils in the pathology of tuberculosis (TB) has been recently established. We demonstrated that TB lesions in man are hypoxic, but how neutrophils in hypoxia influence lung tissue damage is unknown. We investigated the effect of hypoxia on neutrophil-derived enzymes and tissu...

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Bibliografiska uppgifter
I publikationen:Sci Rep
Huvudupphovsmän: Ong, Catherine W. M., Fox, Katharine, Ettorre, Anna, Elkington, Paul T., Friedland, Jon S.
Materialtyp: Artigo
Språk:Inglês
Publicerad: Nature Publishing Group UK 2018
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC6068197/
https://ncbi.nlm.nih.gov/pubmed/30065292
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-018-29659-1
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