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Hypoxia increases neutrophil-driven matrix destruction after exposure to Mycobacterium tuberculosis

The importance of neutrophils in the pathology of tuberculosis (TB) has been recently established. We demonstrated that TB lesions in man are hypoxic, but how neutrophils in hypoxia influence lung tissue damage is unknown. We investigated the effect of hypoxia on neutrophil-derived enzymes and tissu...

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Podrobná bibliografie
Vydáno v:Sci Rep
Hlavní autoři: Ong, Catherine W. M., Fox, Katharine, Ettorre, Anna, Elkington, Paul T., Friedland, Jon S.
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Publishing Group UK 2018
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6068197/
https://ncbi.nlm.nih.gov/pubmed/30065292
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-018-29659-1
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