The interleukin-3 receptor CD123 targeted SL-401 mediates potent cytotoxic activity against CD34(+)CD123(+) cells from acute myeloid leukemia/myelodysplastic syndrome patients and healthy donors

Diseases with clonal hematopoiesis such as myelodysplastic syndrome and acute myeloid leukemia have high rates of relapse. Only a small subset of acute myeloid leukemia patients are cured with chemotherapy alone. Relapse in these diseases occurs at least in part due to the failure to eradicate leuke...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Haematologica
Prif Awduron: Mani, Rajeswaran, Goswami, Swagata, Gopalakrishnan, Bhavani, Ramaswamy, Rahul, Wasmuth, Ronni, Tran, Minh, Mo, Xiaokui, Gordon, Amber, Bucci, Donna, Lucas, David M., Mims, Alice, Brooks, Christopher, Dorrance, Adrienne, Walker, Alison, Blum, William, Byrd, John C., Lozanski, Gerard, Vasu, Sumithira, Muthusamy, Natarajan
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Ferrata Storti Foundation 2018
Pynciau:
Article
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC6068035/
https://ncbi.nlm.nih.gov/pubmed/29773600
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3324/haematol.2018.188193
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