Fc-engineered anti-CD33 monoclonal antibody potentiates cytotoxicity of membrane-bound interleukin-21 expanded natural killer cells in acute myeloid leukemia

BACKGROUND: Qualitative and quantitative defects in natural killer (NK) cells have been noted in patients with acute myeloid leukemia (AML), providing rationale for infusion of donor-derived NK cells. We previously showed that decitabine enhances expression of NKG2D ligands in AML with additive cyto...

Descrición completa

Gardado en:
Detalles Bibliográficos
Publicado en:Cytotherapy
Main Authors: Mani, Rajeswaran, Rajgolikar, Girish, Nunes, Jessica, Zapolnik, Kevan, Wasmuth, Ronni, Mo, Xiaokui, Byrd, John C., Lee, Dean A., Muthusamy, Natarajan, Vasu, Sumithira
Formato: Artigo
Idioma:Inglês
Publicado: 2020
Assuntos:
Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC8176194/
https://ncbi.nlm.nih.gov/pubmed/32303428
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jcyt.2020.02.001
Tags: Engadir etiqueta
Sen Etiquetas, Sexa o primeiro en etiquetar este rexistro!

Títulos similares