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Prevention of prostate cancer by natural product MDM2 inhibitor GS25: in vitro and in vivo activities and molecular mechanisms

Prostate cancer remains a major health problem in the USA and worldwide. There is an urgent need to develop novel approaches to preventing primary and metastatic prostate cancer. We have identified 25-OCH(3)-protopanaxadiol (GS25), the most active ginsenoside that has been identified so far; it has...

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Detalles Bibliográficos
Publicado en:Carcinogenesis
Main Authors: Wang, Wei, Qin, Jiang-Jiang, Li, Xin, Tao, Guanyu, Wang, Qiang, Wu, Xuming, Zhou, Jianwei, Zi, Xiaolin, Zhang, Ruiwen
Formato: Artigo
Idioma:Inglês
Publicado: Oxford University Press 2018
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC6067121/
https://ncbi.nlm.nih.gov/pubmed/29762656
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/carcin/bgy063
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