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Targeting the NFAT1-MDM2-MDMX Network Inhibits the Proliferation and Invasion of Prostate Cancer Cells, Independent of p53 and Androgen

The MDM2 and MDMX oncogenes are overexpressed in various types of human cancer and are highly associated with the initiation, progression, metastasis and chemotherapeutic resistance of these diseases, including prostate cancer. The present study was designed to test a natural MDM2 inhibitor, Inulano...

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Bibliografski detalji
Izdano u:Front Pharmacol
Glavni autori: Qin, Jiang-Jiang, Li, Xin, Wang, Wei, Zi, Xiaolin, Zhang, Ruiwen
Format: Artigo
Jezik:Inglês
Izdano: Frontiers Media S.A. 2017
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5735069/
https://ncbi.nlm.nih.gov/pubmed/29311926
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphar.2017.00917
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