The RNA Methyltransferase Complex of WTAP, METTL3, and METTL14 Regulates Mitotic Clonal Expansion in Adipogenesis

Adipocyte differentiation is regulated by various mechanisms, of which mitotic clonal expansion (MCE) is a key step. Although this process is known to be regulated by cell cycle modulators, the precise mechanism remains unclear. N(6)-Methyladenosine (m(6)A) posttranscriptional RNA modification, whos...

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Veröffentlicht in:Mol Cell Biol
Hauptverfasser: Kobayashi, Masatoshi, Ohsugi, Mitsuru, Sasako, Takayoshi, Awazawa, Motoharu, Umehara, Toshihiro, Iwane, Aya, Kobayashi, Naoki, Okazaki, Yukiko, Kubota, Naoto, Suzuki, Ryo, Waki, Hironori, Horiuchi, Keiko, Hamakubo, Takao, Kodama, Tatsuhiko, Aoe, Seiichiro, Tobe, Kazuyuki, Kadowaki, Takashi, Ueki, Kohjiro
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Microbiology 2018
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Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6066751/
https://ncbi.nlm.nih.gov/pubmed/29866655
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.00116-18
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