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Tyrosine Kinase Signaling in Cancer Metabolism: PKM2 Paradox in the Warburg Effect
The Warburg Effect, or aerobic glycolysis, is one of the major metabolic alterations observed in cancer. Hypothesized to increase a cell's proliferative capacity via regenerating NAD(+), increasing the pool of glycolytic biosynthetic intermediates, and increasing lactate production that affects...
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| Izdano u: | Front Cell Dev Biol |
|---|---|
| Glavni autori: | , |
| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
Frontiers Media S.A.
2018
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| Teme: | |
| Online pristup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6066570/ https://ncbi.nlm.nih.gov/pubmed/30087897 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fcell.2018.00079 |
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