Homology Modeling Informs Ligand Discovery for the Glutamine Transporter ASCT2

The Alanine-Serine-Cysteine transporter (SLC1A5, ASCT2), is a neutral amino acid exchanger involved in the intracellular homeostasis of amino acids in peripheral tissues. Given its role in supplying glutamine to rapidly proliferating cancer cells in several tumor types such as triple-negative breast...

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Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Front Chem
Egile Nagusiak: Garibsingh, Rachel-Ann A., Otte, Nicholas J., Ndaru, Elias, Colas, Claire, Grewer, Christof, Holst, Jeff, Schlessinger, Avner
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Frontiers Media S.A. 2018
Gaiak:
Chemistry
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC6066518/
https://ncbi.nlm.nih.gov/pubmed/30137742
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fchem.2018.00279
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