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Homology Modeling Informs Ligand Discovery for the Glutamine Transporter ASCT2
The Alanine-Serine-Cysteine transporter (SLC1A5, ASCT2), is a neutral amino acid exchanger involved in the intracellular homeostasis of amino acids in peripheral tissues. Given its role in supplying glutamine to rapidly proliferating cancer cells in several tumor types such as triple-negative breast...
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| Pubblicato in: | Front Chem |
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| Autori principali: | , , , , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
Frontiers Media S.A.
2018
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6066518/ https://ncbi.nlm.nih.gov/pubmed/30137742 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fchem.2018.00279 |
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