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Integrin Alpha V Beta 3 Targeted Dendrimer-Rapamycin Conjugate Reduces Fibroblast-Mediated Prostate Tumor Progression and Metastasis

Therapeutic strategies targeting both cancer cells and associated cells in the tumor microenvironment offer significant promise in cancer therapy. We previously reported that generation 5 (G5) dendrimers conjugated with cyclic-RGD peptides target cells expressing integrin alpha V beta 3. In this stu...

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Detalhes bibliográficos
Publicado no:J Cell Biochem
Main Authors: Hill, Elliott E., Kim, Jin Koo, Jung, Younghun, Neeley, Chris K., Pienta, Kenneth J., Taichman, Russell S., Nor, Jacques E., Baker, James R., Krebsbach, Paul H.
Formato: Artigo
Idioma:Inglês
Publicado em: 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6066451/
https://ncbi.nlm.nih.gov/pubmed/29380900
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jcb.26727
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