TBK1 Regulates Prostate Cancer Dormancy through mTOR Inhibition

The mechanisms that regulate hematopoietic stem cell (HSC) dormancy and self-renewal are well established and are largely dependent on signals emanating from the HSC niche. Recently, we found that prostate cancer (PCa) cells target the HSC niche in mouse bone marrow (BM) during metastasis. Little is...

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Detalhes bibliográficos
Main Authors: Kim, Jin Koo, Jung, Younghun, Wang, Jingcheng, Joseph, Jeena, Mishra, Anjali, Hill, Elliott E, Krebsbach, Paul H, Pienta, Kenneth J, Shiozawa, Yusuke, Taichman, Russell S
Formato: Artigo
Idioma:Inglês
Publicado em: Neoplasia Press Inc. 2013
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3769885/
https://ncbi.nlm.nih.gov/pubmed/24027431
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