Disseminated Prostate Cancer Cells Can Instruct Hematopoietic Stem and Progenitor Cells to Regulate Bone Phenotype

Prostate cancer (PCa) metastases and hematopoietic stem cells (HSCs) frequently home to the bone marrow where they compete to occupy the same HSC niche. We have also shown that under conditions of hematopoietic stress, HSCs secrete the bone morphogenetic proteins (BMPs)-2 and BMP-6 that drives osteo...

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Detalhes bibliográficos
Main Authors: Joseph, Jeena, Shiozawa, Yusuke, Jung, Younghun, Kim, Jin Koo, Pedersen, Elisabeth, Mishra, Anjali, Zalucha, Janet Linn, Wang, Jingcheng, Keller, Evan T., Pienta, Kenneth J., Taichman, Russell S.
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3307952/
https://ncbi.nlm.nih.gov/pubmed/22241219
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1541-7786.MCR-11-0404
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