Disseminated Prostate Cancer Cells Can Instruct Hematopoietic Stem and Progenitor Cells to Regulate Bone Phenotype

Prostate cancer (PCa) metastases and hematopoietic stem cells (HSCs) frequently home to the bone marrow where they compete to occupy the same HSC niche. We have also shown that under conditions of hematopoietic stress, HSCs secrete the bone morphogenetic proteins (BMPs)-2 and BMP-6 that drives osteo...

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主要な著者: Joseph, Jeena, Shiozawa, Yusuke, Jung, Younghun, Kim, Jin Koo, Pedersen, Elisabeth, Mishra, Anjali, Zalucha, Janet Linn, Wang, Jingcheng, Keller, Evan T., Pienta, Kenneth J., Taichman, Russell S.
フォーマット: Artigo
言語:Inglês
出版事項: 2012
主題:
Article
オンライン･アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC3307952/
https://ncbi.nlm.nih.gov/pubmed/22241219
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1541-7786.MCR-11-0404
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