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TBK1 Regulates Prostate Cancer Dormancy through mTOR Inhibition

The mechanisms that regulate hematopoietic stem cell (HSC) dormancy and self-renewal are well established and are largely dependent on signals emanating from the HSC niche. Recently, we found that prostate cancer (PCa) cells target the HSC niche in mouse bone marrow (BM) during metastasis. Little is...

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Autori principali: Kim, Jin Koo, Jung, Younghun, Wang, Jingcheng, Joseph, Jeena, Mishra, Anjali, Hill, Elliott E, Krebsbach, Paul H, Pienta, Kenneth J, Shiozawa, Yusuke, Taichman, Russell S
Natura: Artigo
Lingua:Inglês
Pubblicazione: Neoplasia Press Inc. 2013
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3769885/
https://ncbi.nlm.nih.gov/pubmed/24027431
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