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Hypoxia stabilizes GAS6/AXl signaling in metastatic prostate cancer

The receptor tyrosine kinase Axl is over-expressed in a variety of cancers and is known to play a role in proliferation and invasion. Previous data from our lab indicates that Axl and its ligand GAS6 may play a role in establishing metastatic dormancy in the bone marrow microenvironment. In the curr...

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Detalhes bibliográficos
Main Authors: Mishra, Anjali, Wang, Jingcheng, Shiozawa, Yusuke, McGee, Samantha, Kim, Jinkoo, Jung, Younghun, Joseph, Jeena, Berry, Janice E., Havens, Aaron, Pienta, Kenneth J., Taichman, Russell S.
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3378814/
https://ncbi.nlm.nih.gov/pubmed/22516347
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1541-7786.MCR-11-0569
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