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The role of Twist1 in mutant huntingtin–induced transcriptional alterations and neurotoxicity
Huntington's disease (HD) is a fatal neurodegenerative disorder caused by an abnormal expansion of polyglutamine repeats in the huntingtin protein (Htt). Transcriptional dysregulation is an early event in the course of HD progression and is thought to contribute to disease pathogenesis, but how...
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| Publicado no: | J Biol Chem |
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| Main Authors: | , , , , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Biochemistry and Molecular Biology
2018
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6066321/ https://ncbi.nlm.nih.gov/pubmed/29891550 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.RA117.001211 |
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