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The role of Twist1 in mutant huntingtin–induced transcriptional alterations and neurotoxicity

Huntington's disease (HD) is a fatal neurodegenerative disorder caused by an abnormal expansion of polyglutamine repeats in the huntingtin protein (Htt). Transcriptional dysregulation is an early event in the course of HD progression and is thought to contribute to disease pathogenesis, but how...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:J Biol Chem
Egile Nagusiak: Pan, Yanchun, Zhu, Ying, Yang, Wei, Tycksen, Eric, Liu, Shaopeng, Palucki, John, Zhu, Linjian, Sasaki, Yo, Sharma, Mukesh K., Kim, Albert H., Zhang, Bo, Yano, Hiroko
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: American Society for Biochemistry and Molecular Biology 2018
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC6066321/
https://ncbi.nlm.nih.gov/pubmed/29891550
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.RA117.001211
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