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Normal Aging Modulates the Neurotoxicity of Mutant Huntingtin
Aging likely plays a role in neurodegenerative disorders. In Huntington's disease (HD), a disorder caused by an abnormal expansion of a polyglutamine tract in the protein huntingtin (Htt), the role of aging is unclear. For a given tract length, the probability of disease onset increases with ag...
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| Main Authors: | , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Public Library of Science
2009
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2645678/ https://ncbi.nlm.nih.gov/pubmed/19247483 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0004637 |
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