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Evaluation of tafamidis as first-line therapeutic agent for transthyretin familial amyloidotic polyneuropathy

Almost 100 mutations in the human transthyretin (TTR) gene cause the autosomal dominant disorders of familial amyloidotic polyneuropathy (FAP) and familial amyloidotic cardiomyopathy. While these have been clinically classified as separate disorders, the peripheral and autonomic nervous systems and...

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Detalhes bibliográficos
Publicado no:Degener Neurol Neuromuscul Dis
Autor principal: Buxbaum, Joel N
Formato: Artigo
Idioma:Inglês
Publicado em: Dove Medical Press 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6065585/
https://ncbi.nlm.nih.gov/pubmed/30890886
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/DNND.S24624
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