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Evaluation of tafamidis as first-line therapeutic agent for transthyretin familial amyloidotic polyneuropathy

Almost 100 mutations in the human transthyretin (TTR) gene cause the autosomal dominant disorders of familial amyloidotic polyneuropathy (FAP) and familial amyloidotic cardiomyopathy. While these have been clinically classified as separate disorders, the peripheral and autonomic nervous systems and...

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Detalles Bibliográficos
Publicado en:Degener Neurol Neuromuscul Dis
Autor principal: Buxbaum, Joel N
Formato: Artigo
Lenguaje:Inglês
Publicado: Dove Medical Press 2012
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC6065585/
https://ncbi.nlm.nih.gov/pubmed/30890886
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/DNND.S24624
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