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LRP1 is required for novobiocin-mediated fibronectin turnover

Fibronectin (FN) plays a major role in the stability and organization of the extracellular matrix (ECM). We have previously demonstrated that FN interacts directly with Hsp90, as well as showing that the Hsp90 inhibitor novobiocin results in FN turnover via a receptor mediated process. However, the...

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Publicado en:Sci Rep
Autores principales: Boel, Natasha Marie-Eraine, Hunter, Morgan Campbell, Edkins, Adrienne Lesley
Formato: Artigo
Lenguaje:Inglês
Publicado: Nature Publishing Group UK 2018
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC6065439/
https://ncbi.nlm.nih.gov/pubmed/30061663
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-018-29531-2
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