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LRP1 is required for novobiocin-mediated fibronectin turnover

Fibronectin (FN) plays a major role in the stability and organization of the extracellular matrix (ECM). We have previously demonstrated that FN interacts directly with Hsp90, as well as showing that the Hsp90 inhibitor novobiocin results in FN turnover via a receptor mediated process. However, the...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Boel, Natasha Marie-Eraine, Hunter, Morgan Campbell, Edkins, Adrienne Lesley
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6065439/
https://ncbi.nlm.nih.gov/pubmed/30061663
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-018-29531-2
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