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Fibronectin is a stress responsive gene regulated by HSF1 in response to geldanamycin

Fibronectin is an extracellular matrix glycoprotein with key roles in cell adhesion and migration. Hsp90 binds directly to fibronectin and Hsp90 depletion regulates fibronectin matrix stability. Where inhibition of Hsp90 with a C-terminal inhibitor, novobiocin, reduced the fibronectin matrix, treatm...

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Podrobná bibliografie
Vydáno v:Sci Rep
Hlavní autoři: Dhanani, Karim Colin Hassan, Samson, William John, Edkins, Adrienne Lesley
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Publishing Group UK 2017
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5732156/
https://ncbi.nlm.nih.gov/pubmed/29247221
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-18061-y
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