Recurrent Glioblastoma Treated with Recombinant Poliovirus

BACKGROUND: The prognosis of patients with recurrent World Health Organization (WHO) grade IV malignant glioma is dismal, and there is currently no effective therapy. We conducted a dose-finding and toxicity study in this population of patients, evaluating convection-enhanced, intratumoral delivery...

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Dades bibliogràfiques
Publicat a:N Engl J Med
Autors principals: Desjardins, Annick, Gromeier, Matthias, Herndon, James E., Beaubier, Nike, Bolognesi, Dani P., Friedman, Allan H., Friedman, Henry S., McSherry, Frances, Muscat, Andrea M., Nair, Smita, Peters, Katherine B., Randazzo, Dina, Sampson, John H., Vlahovic, Gordana, Harrison, William T., McLendon, Roger E., Ashley, David, Bigner, Darell D.
Format: Artigo
Idioma:Inglês
Publicat: 2018
Matèries:
Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6065102/
https://ncbi.nlm.nih.gov/pubmed/29943666
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1056/NEJMoa1716435
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