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Recurrent Glioblastoma Treated with Recombinant Poliovirus

BACKGROUND: The prognosis of patients with recurrent World Health Organization (WHO) grade IV malignant glioma is dismal, and there is currently no effective therapy. We conducted a dose-finding and toxicity study in this population of patients, evaluating convection-enhanced, intratumoral delivery...

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Detalhes bibliográficos
Publicado no:N Engl J Med
Main Authors: Desjardins, Annick, Gromeier, Matthias, Herndon, James E., Beaubier, Nike, Bolognesi, Dani P., Friedman, Allan H., Friedman, Henry S., McSherry, Frances, Muscat, Andrea M., Nair, Smita, Peters, Katherine B., Randazzo, Dina, Sampson, John H., Vlahovic, Gordana, Harrison, William T., McLendon, Roger E., Ashley, David, Bigner, Darell D.
Formato: Artigo
Idioma:Inglês
Publicado em: 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6065102/
https://ncbi.nlm.nih.gov/pubmed/29943666
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1056/NEJMoa1716435
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