Superinfection and cure of infected cells as mechanisms for hepatitis C virus adaptation and persistence

RNA viruses exist as a genetically diverse quasispecies with extraordinary ability to adapt to abrupt changes in the host environment. However, the molecular mechanisms that contribute to their rapid adaptation and persistence in vivo are not well studied. Here, we probe hepatitis C virus (HCV) pers...

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Bibliografische gegevens
Gepubliceerd in:Proc Natl Acad Sci U S A
Hoofdauteurs: Ke, Ruian, Li, Hui, Wang, Shuyi, Ding, Wenge, Ribeiro, Ruy M., Giorgi, Elena E., Bhattacharya, Tanmoy, Barnard, Richard J. O., Hahn, Beatrice H., Shaw, George M., Perelson, Alan S.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: National Academy of Sciences 2018
Onderwerpen:
PNAS Plus
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6065014/
https://ncbi.nlm.nih.gov/pubmed/29987026
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1805267115
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