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SOCS3 Suppression Promoted the Recruitment of CD11b(+)Gr-1(−)F4/80(−)MHCII(−) Early-Stage Myeloid-Derived Suppressor Cells and Accelerated Interleukin-6-Related Tumor Invasion via Affecting Myeloid Differentiation in Breast Cancer
Interleukin-6 (IL-6) is an important trigger for the expansion and recruitment of myeloid-derived suppressor cells (MDSCs), which are regarded to be major coordinators of the immunosuppressive tumor microenvironment. In this study, we constructed IL-6-knockdown breast cancer mice models to explore t...
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| Wydane w: | Front Immunol |
|---|---|
| Główni autorzy: | , , , , , , , |
| Format: | Artigo |
| Język: | Inglês |
| Wydane: |
Frontiers Media S.A.
2018
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| Hasła przedmiotowe: | |
| Dostęp online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6064721/ https://ncbi.nlm.nih.gov/pubmed/30083161 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2018.01699 |
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