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Spindle tubulin and MTOC asymmetries may explain meiotic drive in oocytes

In the first meiotic division (MI) of oocytes, the cortically positioned spindle causes bivalent segregation in which only the centre-facing homologue pairs are retained. ‘Selfish’ chromosomes are known to exist, which bias their spindle orientation and hence retention in the egg, a process known as...

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Pubblicato in:Nat Commun
Autori principali: Wu, Tianyu, Lane, Simon I. R., Morgan, Stephanie L., Jones, Keith T.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Nature Publishing Group UK 2018
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6063951/
https://ncbi.nlm.nih.gov/pubmed/30054463
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-018-05338-7
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