Symmetry breaking in hydrodynamic forces drives meiotic spindle rotation in mammalian oocytes

Patterned cell divisions require a precisely oriented spindle that segregates chromosomes and determines the cytokinetic plane. In this study, we investigated how the meiotic spindle orients through an obligatory rotation during meiotic division in mouse oocytes. We show that spindle rotation occurs...

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Udgivet i:Sci Adv
Main Authors: Wang, HaiYang, Li, Yizeng, Yang, Jing, Duan, Xing, Kalab, Petr, Sun, Sean X., Li, Rong
Format: Artigo
Sprog:Inglês
Udgivet: American Association for the Advancement of Science 2020
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Research Articles
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7124937/
https://ncbi.nlm.nih.gov/pubmed/32284983
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/sciadv.aaz5004
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