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Spindle tubulin and MTOC asymmetries may explain meiotic drive in oocytes

In the first meiotic division (MI) of oocytes, the cortically positioned spindle causes bivalent segregation in which only the centre-facing homologue pairs are retained. ‘Selfish’ chromosomes are known to exist, which bias their spindle orientation and hence retention in the egg, a process known as...

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書目詳細資料
發表在:Nat Commun
Main Authors: Wu, Tianyu, Lane, Simon I. R., Morgan, Stephanie L., Jones, Keith T.
格式: Artigo
語言:Inglês
出版: Nature Publishing Group UK 2018
主題:
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC6063951/
https://ncbi.nlm.nih.gov/pubmed/30054463
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-018-05338-7
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