Hippo Signaling Pathway Dysregulation in Human Huntington’s Disease Brain and Neuronal Stem Cells

The Hippo signaling pathway is involved in organ size regulation and tumor suppression. Although inhibition of Hippo leads to tumorigenesis, activation of Hippo may play a role in neurodegeneration. Specifically, activation of the upstream regulator, mammalian sterile 20 (STE20)-like kinase 1 (MST1)...

Descripción completa

Guardado en:
Detalles Bibliográficos
Publicado en:Sci Rep
Autores principales: Mueller, Kaly A., Glajch, Kelly E., Huizenga, Megan N., Wilson, Remi A., Granucci, Eric J., Dios, Amanda M., Tousley, Adelaide R., Iuliano, Maria, Weisman, Elizabeth, LaQuaglia, Michael J., DiFiglia, Marian, Kegel-Gleason, Kimberly, Vakili, Khashayar, Sadri-Vakili, Ghazaleh
Formato: Artigo
Lenguaje:Inglês
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC6063913/
https://ncbi.nlm.nih.gov/pubmed/30054496
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-018-29319-4
Etiquetas: Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!

Ejemplares similares