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Pancreatic progenitor-derived hepatocytes are viable and functional in a 3D high density bioreactor culture system

The rat pancreatic progenitor cell line B-13 is of interest for research on drug metabolism and toxicity since the cells trans-differentiate into functional hepatocyte-like cells (B-13/H) when treated with glucocorticoids. In this study we investigated the trans-differentiation and liver-specific fu...

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Publicat a:Toxicol Res (Camb)
Autors principals: Richter, M., Fairhall, E. A., Hoffmann, S. A., Tröbs, S., Knöspel, F., Probert, P. M. E., Oakley, F., Stroux, A., Wright, M. C., Zeilinger, K.
Format: Artigo
Idioma:Inglês
Publicat: Royal Society of Chemistry 2015
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6062372/
https://ncbi.nlm.nih.gov/pubmed/30090344
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c5tx00187k
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