In Vitro Model for Hepatotoxicity Studies Based on Primary Human Hepatocyte Cultivation in a Perfused 3D Bioreactor System

Accurate prediction of the potential hepatotoxic nature of new pharmaceuticals remains highly challenging. Therefore, novel in vitro models with improved external validity are needed to investigate hepatic metabolism and timely identify any toxicity of drugs in humans. In this study, we examined the...

Full beskrivning

Sparad:
Bibliografiska uppgifter
I publikationen:Int J Mol Sci
Huvudupphovsmän: Knöspel, Fanny, Jacobs, Frank, Freyer, Nora, Damm, Georg, De Bondt, An, van den Wyngaert, Ilse, Snoeys, Jan, Monshouwer, Mario, Richter, Marco, Strahl, Nadja, Seehofer, Daniel, Zeilinger, Katrin
Materialtyp: Artigo
Språk:Inglês
Publicerad: MDPI 2016
Ämnen:
Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC4849040/
https://ncbi.nlm.nih.gov/pubmed/27092500
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms17040584
Taggar: Lägg till en tagg
Inga taggar, Lägg till första taggen!

Liknande verk