Defining G protein-coupled receptor peptide ligand expressomes and signalomes in human and mouse islets

INTRODUCTION: Islets synthesise and secrete numerous peptides, some of which are known to be important regulators of islet function and glucose homeostasis. In this study, we quantified mRNAs encoding all peptide ligands of islet G protein-coupled receptors (GPCRs) in isolated human and mouse islets...

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Publicado en:Cell Mol Life Sci
Autores principales: Atanes, Patricio, Ruz-Maldonado, Inmaculada, Hawkes, Ross, Liu, Bo, Zhao, Min, Huang, Guo Cai, Al-Amily, Israa Mohammed, Salehi, Albert, Amisten, Stefan, Persaud, Shanta J.
Formato: Artigo
Lenguaje:Inglês
Publicado: Springer International Publishing 2018
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Original Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC6061145/
https://ncbi.nlm.nih.gov/pubmed/29455414
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00018-018-2778-z
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