The cannabinoid ligands SR141716A and AM251 enhance human and mouse islet function via GPR55-independent signalling

AIMS: Endocannabinoids are lipid mediators involved in the regulation of glucose homeostasis. They interact with the canonical cannabinoid receptors CB(1) and CB(2), and it is now apparent that some cannabinoid receptor ligands are also agonists at GPR55. Thus, CB(1) antagonists such as SR141716A, a...

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Detaylı Bibliyografya
Yayımlandı:Cell Mol Life Sci
Asıl Yazarlar: Ruz-Maldonado, Inmaculada, Liu, Bo, Atanes, Patricio, Pingitore, Attilio, Huang, Guo Cai, Choudhary, Pratik, Persaud, Shanta J.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Springer International Publishing 2020
Konular:
Original Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC7599183/
https://ncbi.nlm.nih.gov/pubmed/31925452
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00018-019-03433-6
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