Defining G protein-coupled receptor peptide ligand expressomes and signalomes in human and mouse islets

INTRODUCTION: Islets synthesise and secrete numerous peptides, some of which are known to be important regulators of islet function and glucose homeostasis. In this study, we quantified mRNAs encoding all peptide ligands of islet G protein-coupled receptors (GPCRs) in isolated human and mouse islets...

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Bibliografske podrobnosti
izdano v:Cell Mol Life Sci
Main Authors: Atanes, Patricio, Ruz-Maldonado, Inmaculada, Hawkes, Ross, Liu, Bo, Zhao, Min, Huang, Guo Cai, Al-Amily, Israa Mohammed, Salehi, Albert, Amisten, Stefan, Persaud, Shanta J.
Format: Artigo
Jezik:Inglês
Izdano: Springer International Publishing 2018
Teme:
Original Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC6061145/
https://ncbi.nlm.nih.gov/pubmed/29455414
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00018-018-2778-z
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